WVE PEER ANALYSIS

Wave Life Sciences Ltd — metric-by-metric comparison with peers and the industry median

WVEWave Life Sciences Ltd

🇺🇸 USA · NASDAQ · Healthcare · Biotechnology

Value it Duel

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile

WVEIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year

Split-adjusted

Year-to-Date (YTD)

Key Metric Comparison

P/E

Lower is better

ROE

Higher is better

Net Margin

Higher is better

Revenue Growth

Higher is better

All Metrics

Valuation
Metric	WVE	MSB	TLX	CSL	RTALB	Ind. Median
P/E	—	—	—	30.02	4.89●	17.81
P/B	2.47	—	6.56	2.24	0.61●	3.49
EV/EBITDA	—	—	123.31	10.37●	74.61	14.92
P/S	17.62	31.91	3.34	2.67●	6.67	10.89

Financial Health
Metric	WVE	MSB	TLX	CSL	RTALB	Ind. Median
Current Ratio	11.26●	—	1.43	2.57	1.21	5.90
Debt/Equity	3.1%	—	112.3%	67.4%	1.2%●	10.9%
NetDebt/EBITDA	3.03	—	13.13	2.22	0.90●	1.15

Profitability
Metric	WVE	MSB	TLX	CSL	RTALB	Ind. Median
Net Margin	-255.7%	-115.3%	-0.9%	9.2%	136.3%●	-125.7%
ROE	-53.7%	-11.3%	-1.8%	7.7%	15.1%●	-47.5%
ROA	-42.1%	-8.6%	-0.7%	3.8%	13.1%●	-35.8%
EBITDA Margin	-243.2%	-76.6%	3.0%	32.8%●	9.0%	-105.8%

Growth + Dividend
Metric	WVE	MSB	TLX	CSL	RTALB	Ind. Median
Rev. Growth	-31.6%	410.4%●	56.3%	4.8%	24.0%	5.1%
NI Growth	—	—	—	-39.4%	134.0%●	12.1%
Div. Yield	—	0.0%	—	2.5%●	0.0%	0.2%
Payout	—	0.0%	—	103.1%	0.0%	0.0%

Valuation
Metric	WVE	ORIC	ARDX	OLMA	EYPT	KALV	Ind. Median
P/E	—	—	—	—	—	—	17.81
P/B	2.47	2.77	8.83	2.73	5.39	-503.31●	3.49
EV/EBITDA	—	—	—	—	—	—	14.92
P/S	17.62	—	3.07●	—	163.08	9.54	10.89

Financial Health
Metric	WVE	ORIC	ARDX	OLMA	EYPT	KALV	Ind. Median
Current Ratio	11.26	16.33●	3.49	10.88	6.66	5.58	5.90
Debt/Equity	3.1%	0.8%	140.1%	0.2%	8.8%	-10,483.5%●	10.9%
NetDebt/EBITDA	3.03	2.08	1.17	2.73	0.78	0.21●	1.15

Profitability
Metric	WVE	ORIC	ARDX	OLMA	EYPT	KALV	Ind. Median
Net Margin	-255.7%	—	-13.6%●	—	-3,566.6%	-78.6%	-125.7%
ROE	-53.7%	-42.6%	-39.5%●	-42.9%	-102.7%	-242.6%	-47.5%
ROA	-42.1%	-39.8%	-12.7%●	-39.4%	-83.5%	-38.4%	-35.8%
EBITDA Margin	-243.2%	—	-6.0%●	—	-3,415.1%	-52.4%	-105.8%

Growth + Dividend
Metric	WVE	ORIC	ARDX	OLMA	EYPT	KALV	Ind. Median
Rev. Growth	-31.6%	-100.0%	18.2%●	-100.0%	-86.4%	—	5.1%
NI Growth	—	—	—	—	—	—	12.1%
Div. Yield	—	—	—	—	—	—	0.2%
Payout	—	—	—	—	—	—	0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

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Data on this page refreshes once per day. Price data as of Jul 6, 26. This content is for informational purposes only and is not investment advice.