VRTX PEER ANALYSIS

Vertex Pharmaceuticals Inc — metric-by-metric comparison with peers and the industry median

VRTXVertex Pharmaceuticals Inc

🇺🇸 USA · US · Healthcare · Biotechnology

Value it Duel

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile

VRTXIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year

Split-adjusted

Year-to-Date (YTD)

Key Metric Comparison

P/E

Lower is better

ROE

Higher is better

Net Margin

Higher is better

Revenue Growth

Higher is better

All Metrics

Valuation
Metric	VRTX	CSL	TLX	Ind. Median
P/E	30.85	29.96●	—	18.06
P/B	6.91	2.24●	6.38	3.62
EV/EBITDA	23.85	10.35●	120.20	15.13
P/S	10.92	2.66●	3.24	10.65

Financial Health
Metric	VRTX	CSL	TLX	Ind. Median
Current Ratio	3.02●	2.57	1.43	5.90
Debt/Equity	10.3%●	67.4%	112.3%	10.9%
NetDebt/EBITDA	-0.98●	2.22	13.13	1.15

Profitability
Metric	VRTX	CSL	TLX	Ind. Median
Net Margin	35.4%●	9.2%	-0.9%	-125.7%
ROE	24.2%●	7.7%	-1.8%	-47.5%
ROA	17.6%●	3.8%	-0.7%	-35.8%
EBITDA Margin	44.0%●	32.8%	3.0%	-105.8%

Growth + Dividend
Metric	VRTX	CSL	TLX	Ind. Median
Rev. Growth	10.4%	4.8%	56.3%●	5.1%
NI Growth	—	-39.4%	—	12.1%
Div. Yield	—	2.5%	—	0.2%
Payout	—	103.1%	—	0.0%

Valuation
Metric	VRTX	REGN	ALNY	RVMD	RPRX	MRNA	Ind. Median
P/E	30.85	16.46●	77.01	—	39.08	—	18.06
P/B	6.91	2.32●	41.34	25.15	4.70	4.25	3.62
EV/EBITDA	23.85	11.62●	46.21	—	23.95	—	15.13
P/S	10.92	4.88●	10.37	—	13.25	14.16	10.65

Financial Health
Metric	VRTX	REGN	ALNY	RVMD	RPRX	MRNA	Ind. Median
Current Ratio	3.02	3.57	3.13	6.80●	2.66	2.41	5.90
Debt/Equity	10.3%	8.6%●	118.4%	29.2%	130.0%	17.5%	10.9%
NetDebt/EBITDA	-0.98	-1.05	-1.88●	1.12	4.91	1.35	1.15

Profitability
Metric	VRTX	REGN	ALNY	RVMD	RPRX	MRNA	Ind. Median
Net Margin	35.4%●	29.6%	13.5%	—	33.9%	-143.6%	-125.7%
ROE	24.2%	14.5%	96.9%●	-76.7%	12.2%	-36.6%	-47.5%
ROA	17.6%●	11.3%	12.4%	-59.4%	4.4%	-26.4%	-35.8%
EBITDA Margin	44.0%	38.5%	21.6%	—	69.6%●	-129.7%	-105.8%

Growth + Dividend
Metric	VRTX	REGN	ALNY	RVMD	RPRX	MRNA	Ind. Median
Rev. Growth	10.4%	5.9%	82.6%●	-100.0%	7.8%	-29.1%	5.1%
NI Growth	—	-1.7%●	—	—	-24.3%	—	12.1%
Div. Yield	—	0.6%	—	—	1.6%●	—	0.2%
Payout	—	8.5%	—	—	46.8%	—	0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

Go deeper on VRTX

Run a DCF valuation

Full DCF model with editable assumptions

Start a head-to-head duel

Compare two stocks metric by metric

Filter in the stock screener

Build your own universe with 400+ metrics

Data on this page refreshes once per day. Price data as of Jul 7, 26. This content is for informational purposes only and is not investment advice.