PTGX PEER ANALYSIS

Protagonist Therapeutics Inc — metric-by-metric comparison with peers and the industry median

PTGXProtagonist Therapeutics Inc

🇺🇸 USA · NASDAQ · Healthcare · Biotechnology

Value it Duel

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile

PTGXIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year

Split-adjusted

Year-to-Date (YTD)

Key Metric Comparison

P/E

Lower is better

ROE

Higher is better

Net Margin

Higher is better

Revenue Growth

Higher is better

All Metrics

Valuation
Metric	PTGX	CSL	TLX	MSB	Ind. Median
P/E	—	30.04	—	—	18.00
P/B	15.06	2.25●	6.26	—	3.60
EV/EBITDA	—	10.37●	118.24	—	15.20
P/S	133.32	2.67●	3.18	30.99	10.43

Financial Health
Metric	PTGX	CSL	TLX	MSB	Ind. Median
Current Ratio	17.76●	2.57	1.43	—	5.90
Debt/Equity	1.5%●	67.4%	112.3%	—	10.9%
NetDebt/EBITDA	4.72	2.22●	13.13	—	1.15

Profitability
Metric	PTGX	CSL	TLX	MSB	Ind. Median
Net Margin	-154.9%	9.2%●	-0.9%	-115.3%	-125.7%
ROE	-17.1%	7.7%●	-1.8%	-11.3%	-47.5%
ROA	-15.9%	3.8%●	-0.7%	-8.6%	-35.8%
EBITDA Margin	-153.8%	32.8%●	3.0%	-76.6%	-105.8%

Growth + Dividend
Metric	PTGX	CSL	TLX	MSB	Ind. Median
Rev. Growth	-64.4%	4.8%	56.3%	410.4%●	5.1%
NI Growth	—	-39.4%	—	—	12.1%
Div. Yield	—	2.5%●	—	0.0%	0.2%
Payout	—	103.1%	—	0.0%	0.0%

Valuation
Metric	PTGX	APGE	CORT	SMMT	IBRX	NUVL	Ind. Median
P/E	—	—	202.62	—	—	—	18.00
P/B	15.06	7.39	15.21	22.03	-10.39●	8.29	3.60
EV/EBITDA	—	—	662.45	—	—	—	15.20
P/S	133.32	—	12.62●	—	64.10	—	10.43

Financial Health
Metric	PTGX	APGE	CORT	SMMT	IBRX	NUVL	Ind. Median
Current Ratio	17.76	32.59●	2.86	7.41	6.67	16.14	5.90
Debt/Equity	1.5%	0.6%	1.5%	3.7%	-129.3%●	—	10.9%
NetDebt/EBITDA	4.72	3.86	-23.21●	0.69	-1.02	—	1.15

Profitability
Metric	PTGX	APGE	CORT	SMMT	IBRX	NUVL	Ind. Median
Net Margin	-154.9%	—	6.2%●	—	-606.2%	—	-125.7%
ROE	-17.1%	-28.5%	7.3%●	-256.3%	—	-41.2%	-47.5%
ROA	-15.9%	-27.4%	5.8%●	-221.2%	-179.8%	-36.9%	-35.8%
EBITDA Margin	-153.8%	—	1.8%●	—	-515.2%	—	-105.8%

Growth + Dividend
Metric	PTGX	APGE	CORT	SMMT	IBRX	NUVL	Ind. Median
Rev. Growth	-64.4%	-100.0%	12.2%	—	351.5%●	—	5.1%
NI Growth	—	—	-64.0%	—	—	—	12.1%
Div. Yield	—	—	—	—	—	—	0.2%
Payout	—	—	—	—	—	—	0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

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Data on this page refreshes once per day. Price data as of Jul 8, 26. This content is for informational purposes only and is not investment advice.