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Financial data sourced from official regulatory filings and verified market data providers. Metrics calculated using GAAP/IFRS standards.

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Last updated: April 2026

NAUT PEER ANALYSIS

Nautilus Biotechnology Inc — metric-by-metric comparison with peers and the industry median

NAUTNautilus Biotechnology Inc

🇺🇸 USA · NASDAQ · Healthcare · Biotechnology

Value itDuel
PriceFinancialsPeers

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile
ValuationProfitabilityGrowthFinancial Health
NAUTIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year
Split-adjusted
NAUT+109.8%RTALB+24.1%MSB+27.6%TLX-28.2%
Year-to-Date (YTD)
NAUT-11.8%RTALB+5.0%MSB-23.5%TLX+55.2%
1-Year
Split-adjusted
NAUT+109.8%CDXS-4.0%VYGR+13.1%ALEC+28.5%IPSC+332.4%IMRX+49.0%
Year-to-Date (YTD)
NAUT-11.8%CDXS+63.2%VYGR-7.9%ALEC+24.4%IPSC+141.3%IMRX-21.9%

Key Metric Comparison

P/E

Lower is better
NAUT—RTALB4.89MSB—TLX—Median 17.81

ROE

Higher is better
NAUT-33.7%RTALB15.1%MSB-11.3%TLX-1.8%Median -47.5%

Net Margin

Higher is better
NAUT—RTALB136.3%MSB-115.3%TLX-0.9%Median -125.7%

Revenue Growth

Higher is better
NAUT-100.0%RTALB24.0%MSB410.4%TLX56.3%Median 5.1%

P/E

Lower is better

ROE

Higher is better
NAUT-33.7%CDXS-68.9%VYGR-52.3%ALEC-238.9%IPSC-42.7%IMRX-0.1%Median -47.5%

Net Margin

Higher is better
NAUT—CDXS-41.0%VYGR-319.6%ALEC-680.8%IPSC—IMRX—Median -125.7%

Revenue Growth

Higher is better
NAUT-100.0%CDXS56.8%VYGR-45.5%ALEC-79.2%IPSC-100.0%IMRX-100.0%Median 5.1%

All Metrics

Valuation
MetricNAUTRTALBMSBTLXInd. Median
P/E—4.89——17.81
P/B1.510.61●—6.563.49
EV/EBITDA—74.61●—123.3114.92
P/S—6.6731.913.34●10.89
Financial Health
MetricNAUTRTALBMSBTLXInd. Median
Current Ratio11.85●1.21—1.435.90
Debt/Equity20.0%1.2%●—112.3%10.9%
NetDebt/EBITDA1.320.90●—13.131.15
Profitability
MetricNAUTRTALBMSBTLXInd. Median
Net Margin—136.3%●-115.3%-0.9%-125.7%
ROE-33.7%15.1%●-11.3%-1.8%-47.5%
ROA-28.2%13.1%●-8.6%-0.7%-35.8%
EBITDA Margin—9.0%●-76.6%3.0%-105.8%
Growth + Dividend
MetricNAUTRTALBMSBTLXInd. Median
Rev. Growth-100.0%24.0%410.4%●56.3%5.1%
NI Growth—134.0%——12.1%
Div. Yield—0.0%●0.0%●—0.2%
Payout—0.0%0.0%—0.0%
Valuation
MetricNAUTCDXSVYGRALECIPSCIMRXInd. Median
P/E——————17.81
P/B1.515.581.2420.670.780.00●3.49
EV/EBITDA——————14.92
P/S—3.09●5.9011.65——10.89
Financial Health
MetricNAUTCDXSVYGRALECIPSCIMRXInd. Median
Current Ratio11.855.368.425.2510.2532.45●5.90
Debt/Equity20.0%168.6%19.9%332.8%18.1%1.8%●10.9%
NetDebt/EBITDA1.32-0.330.951.480.97-60.72●1.15
Profitability
MetricNAUTCDXSVYGRALECIPSCIMRXInd. Median
Net Margin—-41.0%●-319.6%-680.8%——-125.7%
ROE-33.7%-68.9%-52.3%-238.9%-42.7%-0.1%●-47.5%
ROA-28.2%-24.8%-40.7%-38.7%-33.6%-0.1%●-35.8%
EBITDA Margin—-28.2%●-308.4%-632.1%——-105.8%
Growth + Dividend
MetricNAUTCDXSVYGRALECIPSCIMRXInd. Median
Rev. Growth-100.0%56.8%●-45.5%-79.2%-100.0%-100.0%5.1%
NI Growth——————12.1%
Div. Yield——————0.2%
Payout——————0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

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Data on this page refreshes once per day. Price data as of Jul 6, 26. This content is for informational purposes only and is not investment advice.