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Financial data sourced from official regulatory filings and verified market data providers. Metrics calculated using GAAP/IFRS standards.

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Last updated: April 2026

AXSM PEER ANALYSIS

Axsome Therapeutics Inc — metric-by-metric comparison with peers and the industry median

AXSMAxsome Therapeutics Inc

🇺🇸 USA · NASDAQ · Healthcare · Biotechnology

Value itDuel
PriceFinancialsPeers

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile
ValuationProfitabilityGrowthFinancial Health
AXSMIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year
Split-adjusted
AXSM+135.1%CSL-48.2%TLX-29.5%MSB+27.6%
Year-to-Date (YTD)
AXSM+33.8%CSL-28.5%TLX+50.7%MSB-24.3%
1-Year
Split-adjusted
AXSM+135.1%ARWR+397.0%IONS+104.1%BMRN+3.2%KRYS+165.3%TECH+34.0%
Year-to-Date (YTD)
AXSM+33.8%ARWR+26.5%IONS+2.6%BMRN-0.7%KRYS+52.1%TECH+20.8%

Key Metric Comparison

P/E

Lower is better
AXSM—CSL29.44TLX—MSB—Median 17.91

ROE

Higher is better
AXSM-349.4%CSL7.7%TLX-1.8%MSB-11.3%Median -47.5%

Net Margin

Higher is better
AXSM-26.6%CSL9.2%TLX-0.9%MSB-115.3%Median -125.7%

Revenue Growth

Higher is better
AXSM63.9%CSL4.8%TLX56.3%MSB410.4%Median 5.1%

P/E

Lower is better
AXSM—ARWR—IONS—BMRN43.39KRYS50.85TECH101.45Median 17.91

ROE

Higher is better
AXSM-349.4%ARWR-46.4%IONS-67.5%BMRN4.5%KRYS19.9%TECH5.3%Median -47.5%

Net Margin

Higher is better
AXSM-26.6%ARWR-48.4%IONS-30.9%BMRN8.3%KRYS53.9%TECH9.0%Median -125.7%

Revenue Growth

Higher is better
AXSM63.9%ARWR9.4%IONS47.5%BMRN9.9%KRYS25.1%TECH0.2%Median 5.1%

All Metrics

Valuation
MetricAXSMCSLTLXMSBInd. Median
P/E—29.44——17.91
P/B229.142.20●6.37—3.51
EV/EBITDA—10.21●120.14—14.82
P/S17.662.62●3.2431.6110.89
Financial Health
MetricAXSMCSLTLXMSBInd. Median
Current Ratio1.392.57●1.43—5.90
Debt/Equity402.8%67.4%●112.3%—10.9%
NetDebt/EBITDA0.49●2.2213.13—1.15
Profitability
MetricAXSMCSLTLXMSBInd. Median
Net Margin-26.6%9.2%●-0.9%-115.3%-125.7%
ROE-349.4%7.7%●-1.8%-11.3%-47.5%
ROA-28.7%3.8%●-0.7%-8.6%-35.8%
EBITDA Margin-24.4%32.8%●3.0%-76.6%-105.8%
Growth + Dividend
MetricAXSMCSLTLXMSBInd. Median
Rev. Growth63.9%4.8%56.3%410.4%●5.1%
NI Growth—-39.4%——12.1%
Div. Yield—2.5%●—0.0%0.2%
Payout—103.1%—0.0%0.0%
Valuation
MetricAXSMARWRIONSBMRNKRYSTECHInd. Median
P/E———43.39●50.85101.4517.91
P/B229.1419.4827.241.88●8.965.333.51
EV/EBITDA——2.95●22.5552.9643.4014.82
P/S17.6619.2312.653.60●27.429.1810.89
Financial Health
MetricAXSMARWRIONSBMRNKRYSTECHInd. Median
Current Ratio1.396.234.105.819.46●4.495.90
Debt/Equity402.8%223.7%415.3%23.2%0.7%●13.9%10.9%
NetDebt/EBITDA0.493.060.03-1.62-4.06●0.311.15
Profitability
MetricAXSMARWRIONSBMRNKRYSTECHInd. Median
Net Margin-26.6%-48.4%-30.9%8.3%53.9%●9.0%-125.7%
ROE-349.4%-46.4%-67.5%4.5%19.9%●5.3%-47.5%
ROA-28.7%-15.7%-10.4%3.4%18.2%●4.2%-35.8%
EBITDA Margin-24.4%-21.6%433.5%●14.9%48.1%21.3%-105.8%
Growth + Dividend
MetricAXSMARWRIONSBMRNKRYSTECHInd. Median
Rev. Growth63.9%●9.4%47.5%9.9%25.1%0.2%5.1%
NI Growth———-48.7%81.5%●-16.8%12.1%
Div. Yield—0.3%0.2%——0.5%●0.2%
Payout—-13.8%-6.7%——45.5%0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

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Data on this page refreshes once per day. Price data as of Jul 2, 26. This content is for informational purposes only and is not investment advice.