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Financial data sourced from official regulatory filings and verified market data providers. Metrics calculated using GAAP/IFRS standards.

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Last updated: April 2026

AGIO PEER ANALYSIS

Agios Pharm — metric-by-metric comparison with peers and the industry median

AGIOAgios Pharm

🇺🇸 USA · NASDAQ · Healthcare · Biotechnology

Value itDuel
PriceFinancialsPeers

Overall Profile & Returns

· Biotechnology

Position Within Industry

0 = weak quartile, 100 = strong quartile
ValuationProfitabilityGrowthFinancial Health
AGIOIndustry median

Scores normalize each metric against industry quartiles (p25–p75); direction is inverted for lower-is-better metrics.

Return Comparison

1-Year
Split-adjusted
AGIO+3.7%TLX-28.2%MSB+27.6%CSL-47.6%
Year-to-Date (YTD)
AGIO+37.4%TLX+55.2%MSB-23.5%CSL-27.1%
1-Year
Split-adjusted
AGIO+3.7%HRMY+15.1%OCUL+0.4%NUVB+167.9%AUPH+104.1%ADMA-49.9%
Year-to-Date (YTD)
AGIO+37.4%HRMY-1.1%OCUL-20.4%NUVB-37.5%AUPH-2.9%ADMA-49.8%

Key Metric Comparison

P/E

Lower is better
AGIO—TLX—MSB—CSL30.02Median 17.81

ROE

Higher is better
AGIO-32.8%TLX-1.8%MSB-11.3%CSL7.7%Median -47.5%

Net Margin

Higher is better
AGIO-639.8%TLX-0.9%MSB-115.3%CSL9.2%Median -125.7%

Revenue Growth

Higher is better
AGIO78.3%TLX56.3%MSB410.4%CSL4.8%Median 5.1%

P/E

Lower is better
AGIO—HRMY14.94OCUL—NUVB—AUPH7.15ADMA13.29Median 17.81

ROE

Higher is better
AGIO-32.8%HRMY17.9%OCUL-68.6%NUVB-39.5%AUPH65.0%ADMA43.3%Median -47.5%

Net Margin

Higher is better
AGIO-639.8%HRMY16.2%OCUL-558.2%NUVB-102.1%AUPH100.0%ADMA32.4%Median -125.7%

Revenue Growth

Higher is better
AGIO78.3%HRMY20.7%OCUL-12.8%NUVB1,205.5%AUPH20.6%ADMA11.0%Median 5.1%

All Metrics

Valuation
MetricAGIOTLXMSBCSLInd. Median
P/E———30.0217.81
P/B1.98●6.56—2.243.49
EV/EBITDA—123.31—10.37●14.92
P/S33.283.3431.912.67●10.89
Financial Health
MetricAGIOTLXMSBCSLInd. Median
Current Ratio14.19●1.43—2.575.90
Debt/Equity3.2%●112.3%—67.4%10.9%
NetDebt/EBITDA1.68●13.13—2.221.15
Profitability
MetricAGIOTLXMSBCSLInd. Median
Net Margin-639.8%-0.9%-115.3%9.2%●-125.7%
ROE-32.8%-1.8%-11.3%7.7%●-47.5%
ROA-30.8%-0.7%-8.6%3.8%●-35.8%
EBITDA Margin-633.4%3.0%-76.6%32.8%●-105.8%
Growth + Dividend
MetricAGIOTLXMSBCSLInd. Median
Rev. Growth78.3%56.3%410.4%●4.8%5.1%
NI Growth———-39.4%12.1%
Div. Yield——0.0%2.5%●0.2%
Payout——0.0%103.1%0.0%
Valuation
MetricAGIOHRMYOCULNUVBAUPHADMAInd. Median
P/E—14.94——7.15●13.2917.81
P/B1.98●2.393.726.623.765.633.49
EV/EBITDA—7.46●——11.2610.2214.92
P/S33.282.42●41.6014.787.154.3110.89
Financial Health
MetricAGIOHRMYOCULNUVBAUPHADMAInd. Median
Current Ratio14.193.5814.81●7.445.556.955.90
Debt/Equity3.2%22.7%13.7%3.1%●12.1%52.4%10.9%
NetDebt/EBITDA1.68-1.862.144.04-1.92●0.301.15
Profitability
MetricAGIOHRMYOCULNUVBAUPHADMAInd. Median
Net Margin-639.8%16.2%-558.2%-102.1%100.0%●32.4%-125.7%
ROE-32.8%17.9%-68.6%-39.5%65.0%●43.3%-47.5%
ROA-30.8%12.5%-51.0%-26.5%48.5%●28.1%-35.8%
EBITDA Margin-633.4%26.0%-527.0%-90.7%54.2%●43.4%-105.8%
Growth + Dividend
MetricAGIOHRMYOCULNUVBAUPHADMAInd. Median
Rev. Growth78.3%20.7%-12.8%1,205.5%●20.6%11.0%5.1%
NI Growth—-4.7%——648.4%●-20.0%12.1%
Div. Yield——————0.2%
Payout——————0.0%

The green dot marks the best value in the group given the metric direction (higher/lower is better). All metrics use trailing-twelve-month (TTM) data.

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Data on this page refreshes once per day. Price data as of Jul 6, 26. This content is for informational purposes only and is not investment advice.